Journal
BIOCHEMISTRY AND CELL BIOLOGY
Volume 82, Issue 1, Pages 45-61Publisher
CANADIAN SCIENCE PUBLISHING
DOI: 10.1139/o03-086
Keywords
yeast; sphingolipid metabolism; subcellular localization; protein-protein interactions; stress response; aging
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Funding
- NIA NIH HHS [AG16583] Funding Source: Medline
- NIGMS NIH HHS [GM062887] Funding Source: Medline
- NLM NIH HHS [T15LM07438] Funding Source: Medline
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This review of sphingolipid metabolism in the budding yeast Saccharomyces cerevisiae contains information on the enzymes and the genes that encode them, as well as connections to other metabolic pathways. Particular attention is given to yeast homologs, domains, and motifs in the sequence, cellular localization of enzymes, and possible protein-protein interactions. Also included are genetic interactions of special interest that provide clues to the cellular biological roles of particular sphingolipid metabolic pathways and specific sphingolipids.
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