Journal
EXPERIMENTAL EYE RESEARCH
Volume 78, Issue 2, Pages 161-172Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.exer.2003.10.022
Keywords
eye; lens; retina; regeneration; transdifferentiation; stem cells; cataracts; retinal diseases
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Funding
- NEI NIH HHS [R03 EY014197-01, R03 EY014197, EY10540, EY14197] Funding Source: Medline
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In this review we present a synthesis on the potential of vertebrate eye tissue regeneration, such as lens and retina. Particular emphasis is given to two different strategies used for regeneration, transdifferentiation and stem cells. Similarities and differences between these two strategies are outlined and it is proposed that both strategies might follow common pathways. Furthermore, we elaborate on specific clinical applications as the outcome of regeneration-based research (C) 2003 Elsevier Ltd. All rights reserved.
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