Journal
DRUG DEVELOPMENT RESEARCH
Volume 61, Issue 2, Pages 45-65Publisher
WILEY
DOI: 10.1002/ddr.10341
Keywords
tea polyphenols; flavanoids; epigallocatechin gallate; EGCG; theaflavins
Categories
Ask authors/readers for more resources
The medicinal effects of tea (Camellia sinensis) have a long, rich history. The first references to tea date back nearly 5,000 years and are justifiably obscure. Tea has been consumed literally for thousands of years, and it is this long safety record of tea consumption that makes these compounds an attractive target for drug discovery. Much attention has been focused on the role of tea flavanoids in the promotion of health in recent years. However, future studies will need to clarify further the mechanisms of action of these and related compounds, as well as their absorption, metabolism, and potential toxicity. We review here some of the currently available information pertaining to the chemistry, synthesis, pharmacokinetics, and pharmacodynamics of these compounds, which will hopefully serve as a starting point for the continued investigation of these compounds in the clinical setting. Drug Dev. Res. 61:45-65, 2004. (C) 2004 Wiley-Liss, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available