Efficient nucleophilic substitution reactions of highly functionalized allyl halides in ionic liquid media

Nucleophilic substitution reactions of highly functionalized allyl halides with three anions, N-3(-), AcO-, and PhSO2-, in ionic liquid media were conducted. The ionic liquid, [Bmim][BF4], was found to be superior to classical organic solvents to give higher yields and faster reaction rates. The resulting products belong to multifunctionalized trisubstituted alpha,beta-unsaturated ketones, which are useful building blocks for organic synthesis. (C) 2003 Elsevier Ltd. All rights reserved.