Journal
BIOINFORMATICS
Volume 20, Issue 3, Pages 430-432Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btg437
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- NCI NIH HHS [CA 09171] Funding Source: Medline
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Small interfering RNA (siRNA) is used in functional genomics applications to decrease the expression of a target gene, which may yield a biological effect that suggests a function for the target gene. The siRNA design tool scans a target gene for candidate siRNA sequences that satisfy user-adjustable rules. Selected candidates are then screened to identify those siRNA sequences that are specific to the gene of interest.
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