4.5 Article

Synthesis of nitrogen-containing spiro compounds from lactams by allylboration and subsequent ring-closing metathesis

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2004, Issue 4, Pages 812-819

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200300373

Keywords

lactams; boron; nitrogen heterocycles; ring-closing metathesis; spiro compounds

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A series of nitrogen- containing spiro[4]alkenes was prepared with excellent yields starting from lactams in two steps: allylboration on the carbonyl carbon and subsequent ring-closing metathesis of the 2,2-diallyl N-heterocycles. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

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