4.7 Article

A mild and efficient procedure for α-bromination of ketones using N-bromosuccinimide catalysed by ammonium acetate

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 4, Pages 470-471

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b315340a

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Cyclic ketones reacted with N-bromosuccinimide (NBS) catalysed by NH4OAc in Et2O at 25degreesC to give the corresponding alpha-brominated ketones in good yields, while acyclic ketones were efficiently brominated in CCl4 at 80degreesC.

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