Journal
CANCER BIOLOGY & THERAPY
Volume 3, Issue 3, Pages 286-288Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/cbt.3.3.798
Keywords
NF-kappa B; I kappa B; kinase; ubiquitin; E3 ligase; IKK; nemo; CYLD; cancer
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Recent discoveries of the novel roles of lysine 63-linked polyubiquitin chains in the activation of NF-kappaB transcription factor shed new light on both the mechanistic aspects of this signal transduction pathway and its role in cancer.
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