Journal
JOURNAL OF PROTEOME RESEARCH
Volume 3, Issue 2, Pages 253-260Publisher
AMER CHEMICAL SOC
DOI: 10.1021/pr034082c
Keywords
structural proteomics; functional proteomics; quantitative proteomics; mass spectrometry; medicine; oncology
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Advances in proteomics have fundamentally changed the paradigm of discovery for drug targets and novel biomarkers. Proteomics methodologies currently used will be reviewed in this paper, including structural proteomics, quantitative proteomics, and functional proteomics. A strategy to identify differentially expressed cell surface proteins as monoclonal therapeutic targets in oncology will be discussed.
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