Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 42, Issue 3, Pages 1265-1269Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.42.3.1265-1269.2004
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The accessory gene regulator (agr) is a central system that controls the expression of Staphylococcus aureus virulence factors. In this study, the distribution of agr alleles, defined by agr restriction fragment length polymorphism within agr interference groups, among S. aureus isolates from bovine and human origin was measured with PCR-based techniques. Statistically highly significant associations of some agr alleles with the infection of a specific host were found. The genetic difference between the two S. aureus populations was further stressed after analysis of their genetic background by binary typing.
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