Journal
BRITISH JOURNAL OF DERMATOLOGY
Volume 150, Issue 3, Pages 581-588Publisher
WILEY
DOI: 10.1111/j.1365-2133.2004.05838.x
Keywords
apoptosis; colchicine; overdose; skin; toxic epidermal necrolysis
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Colchicine is a microtubule-inhibiting drug used to treat gout, familial Mediterranean fever and many other skin diseases. Intoxication with colchicine affects multiple organs, often fatally. Cutaneous sequelae of colchicine toxicity are rare. We describe the clinical and histological features of a toxic epidermal necrolysis-like exanthem in a patient who lethally overdosed on colchicine.
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