4.4 Article

Synthesis of imidazole-4-carboxylic acids via solid-phase bound 3-N,N-(dimethylamino)-2-isocyanoacrylate

Journal

TETRAHEDRON LETTERS
Volume 45, Issue 10, Pages 2219-2221

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2003.12.158

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The novel 3-N,N-(dimethylamino)isocyanoacrylate-Wang-resin is used for Synthesis of imidazole-4-carboxylic acids. The syntheses are performed in a microwave reactor with reaction times of only 15 min at 220 degreesC in the solvent dimethoxyethane. (C) 2004 Elsevier Ltd. All rights reserved.

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