4.7 Article

New cytotoxic naphthopyrane derivatives from Adenaria floribunda

Journal

JOURNAL OF NATURAL PRODUCTS
Volume 67, Issue 3, Pages 451-453

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/np030223d

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Funding

  1. FIC NIH HHS [1 U01-TW01021-01] Funding Source: Medline

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Bioassay-guided fractionation of an EtOAc/MeOH extract of Adenaria floribunda young leaves using MCF-7, H-460, and SF-268 cancer cell lines yielded four new active compounds named adenaflorins A-D (1-4). Their chemical structures were determined by spectroscopic means. Adenaflorin A (1) was the most cytotoxic.

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