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Recombinant erythropoietin as a neuroprotective treatment: in vitro and in vivo models

Journal

CLINICS IN PERINATOLOGY
Volume 31, Issue 1, Pages 129-+

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.clp.2004.03.004

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Funding

  1. NICHD NIH HHS [HD042213-01] Funding Source: Medline

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The biologic effects of erythropoietin in the central and peripheral nervous system involve the activation of its specific cell surface receptor and corresponding signal transduction pathways. This article reviews the neuroprotective effects of erythropoietin in brain, emphasizing the progress made using in vitro and in vivo research models.

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