4.4 Article

Microarray-based expression analysis of human osteoblast-like cell response to anodized titanium surface

Journal

BIOTECHNOLOGY LETTERS
Volume 26, Issue 5, Pages 399-402

Publisher

SPRINGER
DOI: 10.1023/B:BILE.0000018258.58314.5c

Keywords

DNA microarray; gene expression; heat shock protein 90 (hsp 90); oxide layer; titanium

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An anodized surface significantly enhanced the adhesion of human osteoblast-like MG-63 cells to titanium. Using cDNA microarray analysis, five genes were differentially expressed while the rest remained unaltered. The results demonstrated that the anodized surface enhances cellular adhesion without significantly affecting the pattern of gene expression.

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