Journal
INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE
Volume 8, Issue 1, Pages 37-40Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/13651500310003336
Keywords
treatment; oxcarbazepine; mania
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A twelve-week study examined the efficacy, safety, and tolerability of oxcarbazepine in the treatment of mania. Twenty male subjects, all of whom were stable on valproic acid, qualified for the study. The conversion from valproic acid to oxcarbazepine was completed over a three-week period. Scores from the BPRS, CGI and SATEE-GI were collected and analyzed. The results of the study supported the efficacy, safety, and tolerability of oxcarbazepine for the treatment of mania. Another potential advantage of oxcarbazepine is a metabolic pathway that may reduce drug interactions.
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