Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 12, Issue 5, Pages 1047-1053Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2003.12.014
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2-(6-aryl-3-hexen-1,5-diynyl)benzonitriles 3a-j showed growth inhibition effects on a full panel of 60 human cancer cell lines in low micro-concentrations, in which compounds 3c,d displayed a significant G2/M arrest in the cell growth cycle compared with other derivatives and an apoptotic progress induction were also shown by 3a-d. (C) 2004 Elsevier Ltd. All rights reserved.
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