Journal
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Volume 50, Issue 3, Pages 357-362Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jaad.2003.09.024
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Background: Very little has been published On whether a relationship exists between atopic dermatitis (AD) and skin cancer. Objective: The goal of this study was to investigate whether individuals with AD are more likely than other patients with dermatologic conditions to develop nonmelanoma skin cancer. Methods: This was a case-control, mailed-survey study. Results: 017 those contacted, 69.8% (3207 of 4591) filled out the survey. Of the control patients, 18.4% (254) had a history of AD as defined by the United Kingdom Working Party diagnosis criteria and composed 13.7% (210) of the cases. The unadjusted Odds ratio of AD to nonmelanoma skin cancer was 0.70 (95% confidence interval 0.57-0.85). After fully adjusting for age, sex, ethnicity, and topical steroid use the odds ratio was 0.78 (0.61, 0.98). Using different definitions of AD had little effect on this result. Conclusions: It does not appear that patients with a history of AD are more likely to develop nonmelanoma skin cancers dian other patients with dermatologic conditions.
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