Journal
NEUROREPORT
Volume 15, Issue 3, Pages 431-436Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001756-200403010-00010
Keywords
cardiovascular control; dopamine beta-hydroxylase; double immunofluorescence microscopy; fever; immunoelectron microscopy; intermediolateral cell column; lateral horn; sympathetic nervous system; thermoregulation; vesicular glutamate transporter
Categories
Ask authors/readers for more resources
To characterize glutamatergic axon terminals onto sympathetic preganglionic neurons (SPNs), we visualized immunohistochemically three vesicular glutamate transporters (VGLUTs) in the intermediolateral cell column (IML) of rat thoracic spinal cord. VGLUT2 and VGLUT3 immunoreactivities but not VGLUT1 immunoreactivity were distributed in the IML and found in terminals making asymmetric synapses and apposed to dendrites immunopositive for choline acetyltransferase, an SPN marker. VGLUT2 and VGLUT3 immunoreactivities were not co-localized with each other. A population of VGLUT2-immunoreactive but not VGLUT3-immunoreactive terminals were adrenergic or noradrenergic. Some of VGLUT3-immunoreactive but not VGLUT2-immunoreactive terminals contained serotonin. These results indicate at least two independent glutamatergic terminal populations, which include a distinct monoaminergic subpopulation, making excitatory inputs onto SPNs.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available