Journal
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
Volume 9, Issue 2, Pages 119-123Publisher
SPRINGER
DOI: 10.1007/s00775-003-0519-7
Keywords
oxidative stress; superoxide; superoxide dismutase; superoxide reductase
Ask authors/readers for more resources
For more than 30 years, the only enzymatic system known to catalyze the elimination of superoxide was superoxide dismutase, SOD. SOD has been found in almost all organisms living in the presence of oxygen, including some anaerobic bacteria, supporting the notion that superoxide is a key and general component of oxidative stress. Recently, a new concept in the field of the mechanisms of cellular defense against superoxide has emerged. It was discovered that elimination of superoxide in some anaerobic and microaerophilic bacteria could occur by reduction, a reaction catalyzed by a small metalloenzyme thus named superoxide reductase, SOR. Having played a major role in this discovery, we describe here how the concept of superoxide reduction emerged and how it was experimentally substantiated independently in our laboratory.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available