Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 39, Issue 3, Pages 267-272Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2003.11.001
Keywords
thiazole; benzothiazole; benzimidazole; benzoxazole; antimicrobial activity
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Some 2-[(benzazole-2-yl)thioacetylamino]thiazole derivatives (III) were synthesized by reacting 4-methyl-2-(chloroacetylamino)thiazole derivatives (I) with benzazol-2-thiole (II) in acetone in the presence of K2CO3. The chemical structures of the compounds were elucidated by H-1 NMR and FAB(+)-MS spectral data. The prepared compounds were tested for antimicrobial activity and toxicity. (C) 2003 Elsevier SAS. All rights reserved.
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