Mean ovarian diameter (MOD) as a predictor of poor ovarian response

Purpose: To determine the predictive value of mean ovarian diameter of ovarian response in controlled ovarian hyperstimulation (COH), in outcome with normal FSH level in early follicular phase of menstrual cycle. Methods: A prospective study established the prognostic value of the mean ovarian diameter of total 57 cases, including 17 patients undergoing IVF treatment with poor ovarian response and 40 patients ( control group) with adequate ovarian response. Results: The mean ovarian diameter ( MOD) of patients in the cancelled group was significantly lower (19.23 +/- 2.78) than in a comparable control group (24.67 +/- 3.38) [p < 0.001]. The mean ovarian diameter was a good predictor of poor ovarian response - area under receiver operating characteristic curve - ROCAUC = 0.88. The best criterion value discriminating between cancelled cycle and punctured was <= 20.6 mm. Conclusions: Our data demonstrate that the mean ovarian diameter provides good prognostic information in outcomes with poor ovarian response during controlled ovarian hyperstimulation in IVF. The test is easy to perform and it is a good informative resource.