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Kinesins and protein kinases: Key players in the regulation of microtubule dynamics and organization

Journal

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Volume 510, Issue 2, Pages 83-92

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.abb.2011.02.012

Keywords

Kinesin; Microtubule dynamics; Protein kinase; Cellular signaling; Mitotic spindle; Cilium

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Microtubule dynamics is controlled and amplified in vivo by complex sets of regulators. Among these regulatory proteins, molecular motors from the kinesin superfamily are taking an increasing importance. Here we review how microtubule disassembly or assembly into interphase microtubules, mitotic spindle or cilia may involve kinesins and how protein kinases may participate in these kinesin-dependent regulations. (C) 2011 Elsevier Inc. All rights reserved.

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