Journal
ORGANIC LETTERS
Volume 6, Issue 5, Pages 819-821Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol049956v
Keywords
-
Categories
Ask authors/readers for more resources
A highly efficient one-pot procedure for 3-sulfenylation of 2-carboxyindoles is described. Treatment of thiols with N-chlorosuccinimide at -78 degreesC in CH2Cl2 affords sulfenyl chlorides in situ that readily react with 2-carboxyindoles to give 3-thioindoles in high yields. This new method is milder, produces less waste, and is compatible with a wide range of thiol and indole functionality.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available