4.4 Article

Basic alumina catalysed synthesis of substituted 2-amino-2-chromenes via three-component reaction

Journal

TETRAHEDRON LETTERS
Volume 45, Issue 11, Pages 2297-2299

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.01.115

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Substituted 2-amino-2-chromenes were obtained in excellent yield and selectivity simply by mixing malononitrile, alpha-naphthol and aromatic aldehydes in water in the presence of basic alumina as heterogeneous and reusable catalyst. (C) 2004 Elsevier Ltd. All rights reserved.

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