Journal
BRAIN RESEARCH
Volume 1000, Issue 1-2, Pages 40-56Publisher
ELSEVIER
DOI: 10.1016/j.brainres.2003.10.073
Keywords
nociception; afferent pain pathway; tract; supraspinal projection; cortical structure
Categories
Funding
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [98/14303-3] Funding Source: FAPESP
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Painful experience is a complex entity made up of sensory, affective, motivational and cognitive dimensions. The neural mechanisms involved in pain perception acts in a serial and a parallel way, discriminating and locating the original stimulus and also integrating the affective feeling, involved in a special situation, with previous memories. This review examines the concepts of nociception, acute and chronic pain, and also describes the afferent pathways involved in reception, segmental processing and encephalic projection of pain Stimulus. The interaction model of the cerebral cortex areas and their functional characteristics are also discussed. (C) 2004 Elsevier B.V. All rights reserved.
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