4.4 Article

A facile synthesis of 1,7-dicarbonyl compounds via three-component Michael addition reactions

Journal

TETRAHEDRON LETTERS
Volume 45, Issue 12, Pages 2649-2651

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.01.137

Keywords

1,7-dicarbonyl; three-component; Michael addition; nitromethane; alpha,beta-unsaturated carbonyl compounds

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A convenient one-pot synthesis of 1,7-dicarbonyl compounds has been accomplished by a three-component Michael addition reaction of nitromethane with two unsymmetric alpha,beta-unsaturated carbonyl compounds in the presence of a base. (C) 2004 Elsevier Ltd. All rights reserved.

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