Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 14, Issue 2, Pages 147-154Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2004.02.009
Keywords
-
Categories
Ask authors/readers for more resources
Histone acetyltransferase complexes have been shown to be key regulators of gene expression. Among these, the NuA4 complex, first characterized in yeast, stands out as it controls multiple key nuclear functions in eukaryotic cells. Many subunits of this protein assembly have been directly linked to global and targeted acetylation of histone H4 tails in vivo, regulation of transcription, cell-cycle progression as well as to the process of DNA repair. Recent studies presented here have established its remarkable structural conservation from yeast to human cells and contributed to the understanding of its diverse functions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available