Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 14, Issue 2, Pages 165-173Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2004.01.007
Keywords
-
Categories
Ask authors/readers for more resources
ATP-dependent chromatin remodelling enzymes act to alter chromatin structure during gene regulation. Studies of the ATPase motors that drive these enzymes support the notion that they function as ATP-dependent DNA translocases with limited processivity. The action of these enzymes on nucleosomes results in the alteration of nucleosome positioning and structure. Recent studies have shown that ATP-dependent chromatin remodelling can also either remove or exchange histone dimers between nucleosomes. This provides a new means by which the incorporation of histone variants can be directed. Additional observations support roles for ATP-dependent remodelling enzymes throughout the transcription cycle.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available