3.8 Article

Implementation of the prostate cancer prevention trial (PCPT)

Journal

CONTROLLED CLINICAL TRIALS
Volume 25, Issue 2, Pages 203-222

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.cct.2003.11.007

Keywords

study organization; study management; chemoprevention; prostate cancer; finasteride

Funding

  1. NCI NIH HHS [CA38926, 5U10-CA37429] Funding Source: Medline

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The Prostate Cancer Prevention Trial is a randomized double blind chemoprevention trial of 18,882 men. It is designed to test the difference in the histologically proven prostate cancer prevalence between a group of participants given finasteride and another given placebo for 7 years. We present an overview of the study design, details of the administrative structure of the study and a description of the successful implementation of the accrual phase. (C) 2004 Elsevier Inc. All rights reserved.

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