Journal
RESPIRATORY MEDICINE
Volume 98, Issue 4, Pages 330-333Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.rmed.2003.11.002
Keywords
obstructive sleep apnea; hypopnea; auto-titrating CPAP; fixed CPAP; compliance; efficacy; side effects
Ask authors/readers for more resources
Background: Continuous positive airway pressure (CPAP) remains the treatment of choice for obstructive steep apnea-hypopnea (OSAH). Auto-titrating CPAP (APAP) devices automatically adjust pressure and may improve treatment compliance compared to fixed CPAP (F-CPAP). Methods: Randomized, prospective, single-blind, crossover trial to compare efficacy, side effects, compliance, patient satisfaction and preference between APAP and F-CPAP therapy in patients with moderate to severe OSAH. There were two treatment periods of 4 weeks each (APAP and F-CPAP), separated by a 2-week washout period. Results: Ten CPAP-naive OSAH patients (9 mates) completed the study. They had Mean +/- SD age of 44.9 +/- 9.7 years; body mass index of 35.9 +/- 12.9 kg/m(2) and apnea/hypopnea index (AHI) of 47.2 +/- 35.6. Both forms of therapy were equally effective in improving the symptoms and in reducing the AHI. Both forms of therapy were associated with frequent side effects and had similar patient compliance. At the end of the study, more patients (6-1) preferred F-CPAP to A-CPAP therapy. Conclusion: A-PAP was as effective as F-CPAP in the treatment of OSAH but was not associated with fewer side effects, better compliance, better satisfaction or increased patient preference. (C) 2003 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available