4.5 Article

Oligodendrocyte precursors on the move: Mechanisms directing migration

Journal

NEUROSCIENTIST
Volume 10, Issue 2, Pages 99-105

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/1073858403260751

Keywords

motility; laminin; fibronectin; vitronectin; tenascin; collagen; netrin; semaphorin; PDGF; FGF; HGF

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Oligodendrocyte precursor cells traverse long distances to reach their axonal targets. The molecules that influence their migration include a combination of short-range attractants and repellents and long-range chemoattractants and chemorepellents. Here, the authors review mechanisms that direct oligodendrocyte precursor cells as they migrate throughout the developing CNS.

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