Journal
JOURNAL OF BACTERIOLOGY
Volume 186, Issue 7, Pages 2212-2214Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.186.7.2212-2214.2004
Keywords
-
Categories
Ask authors/readers for more resources
It has recently been proposed that phenotypic variation in clonal populations of bacterial species results from intracellular noise, i.e., random fluctuations in levels of cellular molecules, which would be predicted to be insensitive to selective pressure. To test this notion, we propagated five populations of Bacillus subtilis for 5,000 generations with selection for one phenotype: the decision to sporulate. In support of the noise hypothesis, we report that none of the populations responded to selection by improving their efficiency of sporulation, indicating that intracellular noise is independent of heritable genotype.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available