Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 68, Issue 4, Pages 868-872Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.68.868
Keywords
protein-alpha-1,3-glucan complex; anti-tumor activity; NMR; mycelia; Phellinus linteus
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All the fractions of Phellinus linteus mycelia showed anti-tumor activity toward solid tumors planted in mice. The highest anti-tumor activity of 81.2% was observed in the protein-glucan complex obtained by precipitating the 24% NaOH extract at pH 6.0. This protein-glucan complex consisted of 39.3% polysaccharide and 49.4% protein. Its C-13- and H-1-NMR data showed that the main glucan part of the complex was simple alpha-1,3-glucan chains.
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