4.4 Article Proceedings Paper

The hyperthermophilic origin of life revisited

Journal

BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 32, Issue -, Pages 168-171

Publisher

PORTLAND PRESS LTD
DOI: 10.1042/BST0320168

Keywords

biogenesis; hyperthermophile; last common ancestor (LCA); reverse gyrase

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We revisit the case for the hyperthermophilic scenario for the origin of life and the last common ancestor. Evidence includes studies of phylogenetic trees, rRNA, G and C content, hyperthermophilic proteins, correlations between maximal temperature tolerances and genetic distances, saline stabilization of DNA/RNA, and the inferred climatic temperatures of the early Earth. Although some doubts remain, the case for hot biogenesis and the last common ancestor has gotten stronger.

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