Journal
MICROBES AND INFECTION
Volume 6, Issue 4, Pages 390-397Publisher
ELSEVIER
DOI: 10.1016/j.micinf.2003.12.008
Keywords
Staphylococcus aureus; heme; hemoproteins; iron-regulated surface determinants; sortase; iron
Categories
Funding
- NIAID NIH HHS [AI38897, AI52474] Funding Source: Medline
Ask authors/readers for more resources
Cell-wall sorted proteins of the Staphylococcus aureus iron-regulated surface determinant system bind human hemoproteins, remove the heme molecule, and transport heme through the cell wall and plasma membrane for accumulation in the bacterial cytoplasm. Once inside the cell, the porphyrin ring of heme is degraded by heme degrading monooxygenases, leading to the formation of free iron for use by the bacterium as a nutrient source. (C) 2004 Elsevier SAS. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available