4.8 Article

Rhodium-catalyzed addition/ring-opening reaction of arylboronic acids with cyclobutanones

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ORGANIC LETTERS
Volume 6, Issue 8, Pages 1257-1259

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AMER CHEMICAL SOC
DOI: 10.1021/ol049833a

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[GRAPHICS] Cyclobutanones react with arylboronic acids in the presence of a catalytic amount of Rh(l) complex to afford butyrophenone derivatives through the addition of an arylrhodium(l) species to the carbonyl group, followed by ring-opening of the resulting rhodium(l) cyclobutanolate.

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