4.5 Article

The cis-specific Pictet-Spengler reaction

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2004, Issue 9, Pages 1887-1890

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200400017

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The Pictet-Spengler reaction of tryptophan allyl ester with aryl aldehydes generates cis-tetrahydro-beta-carbolines with complete stereo-control and with complete retention of optical integrity, when the reaction is carried out under kinetically controlled conditions. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).

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