4.8 Article

Catechol-based phosphoramidites: A new class of chiral ligands for rhodium-catalyzed asymmetric hydrogenations

Journal

ORGANIC LETTERS
Volume 6, Issue 9, Pages 1433-1436

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol049726g

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The synthesis and application of a new class of catechol-based phosphoramidites is described. Ees up to 99% were obtained in the rhodium-catalyzed asymmetric hydrogenation of dehydroamino acids and enamides.

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