4.3 Article

A novel podophyllotoxin lignan from Justicia heterocarpa

Journal

CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 52, Issue 5, Pages 507-509

Publisher

PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.52.507

Keywords

Justicia heterocarpa; Acanthaceae; podophyllotoxin lignan; X-ray analysis

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Chromatographic separation of the extract of Justicia heterocarpa T. ANDERS. afforded, in addition to known fatty acids, terpenoids and steroids, a new podophyllotoxin lignan. Structures were elucidated by spectroscopic methods, and the structure of the new lignan was confirmed by single crystal X-ray diffraction studies, which have shown that there is a H-bonding stabilized dimer.

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