Journal
CURRENT MEDICAL RESEARCH AND OPINION
Volume 20, Issue 5, Pages 645-649Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1185/030079904125003575
Keywords
baby; barrier; emollients; irritant diaper dermatitis; moisturisers; nappy rash; skin; skin care; stratum corneum
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Irritant diaper dermatitis (IDD) is a form of contact dermatitis occurring in the diaper area as a consequence of disruption of the barrier function of the skin through prolonged contact with faeces and urine. Despite advances in diaper technology, it is a condition that still occurs regularly in young children. To combat this, barrier preparations can be used to protect the skin by coating the surface of the skin and/or by supplying lipids that can penetrate the intercellular spaces of the stratum corneum. In this review, the pathophysiology of IDD is outlined and its prevention and treatment are discussed, with particular reference to the role of emollients.
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