Journal
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
Volume 97, Issue 5, Pages 293-296Publisher
OXFORD UNIV PRESS
DOI: 10.1093/qjmed/hch050
Keywords
-
Categories
Ask authors/readers for more resources
Background: Although it is widely assumed that dehydration predisposes to venous thromboembolism (VTE), there are no clinical studies to support this. Aim: To evaluate the relationship between biochemical indices of dehydration and VTE after acute ischaemic stroke (AIS). Design: Prospective observational study. Methods: Unselected AIS patients (n=102) receiving standard thromboprophylaxis with aspirin and graded compression stockings, underwent serial measurements of serum urea, creatinine and osmolality, and were screened for VTE using magnetic resonance direct thrombus imaging. Results: Serum osmolality of >297 mOsm/kg, urea >7.5 mmol/l and urea:creatinine ratio (mmol:mmol) >80 a few days post-AIS were associated with odds ratios for VTE of, respectively, 4.7, 2.8 and 3.4 (p = 0.02, 0.05, 0.02) on multivariable analysis. Discussion: Dehydration after AIS is strongly independently associated with VTE, reinforcing the importance of maintaining adequate hydration in these patients.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available