4.7 Article

Dissolved humic substances initiate DNA-methylation in cladocerans

Journal

AQUATIC TOXICOLOGY
Volume 105, Issue 3-4, Pages 640-642

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.aquatox.2011.08.025

Keywords

DNA-methylation; Humic substances; Daphnia magna; Moina macrocopa

Funding

  1. German Research Foundation (DFG) [STE 673/16-1]

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DNA-methylation is one pathway of epigenetic programming of gene expression and can be responsive to environmental challenges such as methylating agents in the food. Here we report on the DNA-methylation in the cladocerans Daphnia magna and Moina macrocopa exposed to humic substances, ubiquitous biogeochemicals. The methylation of DNA can alter the stress response, presumably including exposure to synthetic xenobiotic chemicals. (C) 2011 Elsevier B.V. All rights reserved.

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