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C/EBPα mutations in acute myeloid leukaemias

Journal

NATURE REVIEWS CANCER
Volume 4, Issue 5, Pages 394-400

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NATURE PUBLISHING GROUP
DOI: 10.1038/nrc1363

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Specific mutations in the gene that encodes the multifunctional transcription factor C/EBPalpha are frequently associated with acute myeloid leukaemias. Are only a specific subset of the functions of C/EBPalpha therefore involved in leukaemogenesis?

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