Journal
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 19, Issue 5, Pages 737-744Publisher
AMER SOC BONE & MINERAL RES
DOI: 10.1359/JBMR.040209
Keywords
clinical trials; osteoporosis; treatments; bone densitometry; bone turnover markers
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To study effects of statins on human bone, 82 postmenopausal women were randomized to I-year treatment with simvastatin 40 mg/day or placebo. The study showed no effect of simvastatin on biochemical bone markers or on BMD at the hip or spine. Thus, our results do not support a general beneficial effect of simvastatin on bone.
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