4.7 Article

Comparison of an inflammation-based prognostic score (GPS) with performance status (ECOG) in patients receiving platinum-based chemotherapy for inoperable non-small-cell lung cancer

Journal

BRITISH JOURNAL OF CANCER
Volume 90, Issue 9, Pages 1704-1706

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6601789

Keywords

systemic inflammatory response; prognostic score; stage; performance status; survival; chemotherapy; non-small-cell lung cancer

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The value of an inflammation-based prognostic score (GPS) was compared with performance status (ECOG) in patients (n = 109) receiving platinum-based chemotherapy for inoperable non-small-cell lung cancer. On multivariate analysis with ECOG, white cell count and the GPS entered as covariates, only the GPS was a significant independent predictor of survival (HR 1.88, 95% CI 1.25-2.84, P = 0.002).

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