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Piperazine-based CCR5 antagonists as HIV-1 inhibitors.: IV.: Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[4-{2-methoxy-1(R)-4-(trifluoromethyl)-phenyl}ethyl-3(S)-methyl-1-piperazinyl]-4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist
JOURNAL OF MEDICINAL CHEMISTRY (2004)
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