4.8 Article

Copper(II) acetate promoted oxidative cyclization of arylsulfonyl-o-allylanilines

Journal

ORGANIC LETTERS
Volume 6, Issue 10, Pages 1573-1575

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol049702+

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Tosyl-o-allylaniline 1 undergoes oxidative cyclization to produce tetracycle 2 upon treatment with Cu(OAc)(2) and Cs2CO3 at 120 degreesC. The scope of the reaction was extended to other N-sulfonylated aromatic systems.

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