Journal
BRITISH JOURNAL OF CANCER
Volume 90, Issue 10, Pages 1972-1975Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6601776
Keywords
MBD3; colon cancer; lung cancer; mutation; methylation
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MBD3 is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alteration in these cancers. (C) 2004 Cancer Research UK.
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