4.6 Article

Anticonvulsant activity of Mimosa pudica decoction

Journal

FITOTERAPIA
Volume 75, Issue 3-4, Pages 309-314

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2004.01.012

Keywords

Mimosa pudica; anticonvulsant; sedative; seizures

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The decoction of Mimosa pudica leaves given intraperitoneally at dose of 1000-4000 mg/kg protected mice against pentylentetrazol and strychnine-induced seizures. M. pudica had no effect against picrotoxin-induced seizures It also antagonized N-methyl-D-aspartate-induced turning behavior. These properties could explain its use in African traditional medicine. (C) 2004 Elsevier B.V. All rights reserved.

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